Assessment of myocardial oxygenation in patients with severe aortic stenosis before and after aortic valve replacement: an oxygenation-sensitive CMR study
نویسندگان
چکیده
Background Left ventricular hypertrophy in aortic stenosis (AS) is characterised by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, it remains unclear whether the hypoperfusion seen in severe AS leads to myocardial tissue deoxygenation and thus, ischemia during stress. The aim of this study was to assess myocardial oxygenation and perfusion in patients with severe AS but no obstructive coronary artery disease before and after aortic valve replacement (AVR).
منابع مشابه
Myocardial perfusion and oxygenation are impaired during stress in severe aortic stenosis and correlate with impaired energetics and subclinical left ventricular dysfunction
BACKGROUND Left ventricular (LV) hypertrophy in aortic stenosis (AS) is characterized by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, whether this hypoperfusion leads to tissue deoxygenation is unknown. We aimed to assess myocardial oxygenation in severe AS without obstructive coronary artery disease, and to investigate its association with myocardial...
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